Selasa, 19 November 2013

Biologists ID new cancer weakness

MIT News - 4 hari yang lalu
About half of all cancer patients have a mutation in a gene called p53, which allows tumors to survive and continue growing even after chemotherapy severely damages their DNA. A new study from MIT biologists has found that tumor cells with mutated p53 can be made much more vulnerable to chemotherapy by blocking another gene called MK2. In a study of mice, tumors lacking both p53 and MK2 shrank dramatically when treated with the drug cisplatin, while tumors with functional MK2 kept growing after treatment. The findings suggest that giving cancer patients a combination of a DNA-dama... lainnya »

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